Sperm DNA Fragmentation Test in Mumbai | Advanced Male Fertility Check

What is a Sperm DNA Fragmentation Test?
A sperm DNA fragmentation test is a specialized assessment that evaluates the integrity of DNA in sperm cells. Unlike a standard semen analysis, which measures sperm count, motility, and morphology, this test focuses on the quality of genetic material. Detecting DNA fragmentation is important because high levels can affect fertilization, embryo quality, and overall fertility outcomes.
Why is DNA Testing Important in Male Fertility?
Even if sperm count and motility appear normal, DNA damage can reduce the chances of successful conception or increase the risk of miscarriage. A sperm DNA fragmentation test provides detailed insight into sperm quality and helps fertility specialists design personalized treatment plans, improving the success of IVF, IUI, or ICSI procedures.
How is the Semen Sample Collected and Tested?
The procedure for a sperm DNA fragmentation test is similar to a standard semen analysis. The sample is collected through masturbation in a sterile container and then analyzed in the laboratory. The test measures the percentage of sperm with fragmented DNA and evaluates overall sperm health.
Key steps include:
Collecting the sample after 2–5 days of abstinence
Laboratory assessment of DNA integrity
Reporting results with a fragmentation index (DFI)
This ensures accurate evaluation and guides fertility specialists in recommending the most effective interventions.
What Does the Sperm DNA Fragmentation Report Show?
The sperm DNA fragmentation test report provides information about the percentage of sperm with damaged DNA. High DNA fragmentation may indicate oxidative stress, lifestyle factors, or underlying medical conditions. These results help fertility specialists decide whether interventions such as antioxidants, lifestyle changes, or advanced reproductive techniques like ICSI are needed.
How Should I Prepare Before the Test?
Proper preparation is important to ensure accurate results from a sperm DNA fragmentation test. Recommendations include:
Abstaining from ejaculation for 2–5 days before the test
Avoiding alcohol, smoking, and excessive caffeine
Maintaining a healthy diet and lifestyle
Following any specific instructions from your fertility clinic
What If My DNA Fragmentation Level is High?
If the sperm DNA fragmentation test shows high levels, fertility specialists may suggest:
Lifestyle modifications including diet, exercise, and stress reduction
Antioxidant supplementation to improve sperm quality
Assisted reproductive techniques such as ICSI, which may bypass sperm DNA issues
Regular monitoring with follow-up sperm DNA fragmentation tests to track improvement
How Often Should I Repeat the Test?
Depending on the initial results and ongoing fertility treatment, the sperm DNA fragmentation test may be repeated every 3–6 months. Repeat testing helps monitor improvement, evaluate the effectiveness of interventions, and ensure optimal conditions for conception.
How Does Meridian IVF Help with Male Fertility Issues?
At Meridian IVF, we use advanced sperm DNA fragmentation tests to assess male fertility in detail. Our experts provide personalized guidance, combining medical, lifestyle, and assisted reproductive strategies to improve sperm quality. Regular monitoring with sperm DNA fragmentation tests ensures couples receive precise recommendations for successful conception.
Book Your Sperm DNA Fragmentation Test Appointment
Scheduling a sperm DNA fragmentation test at Meridian IVF is simple. Our team ensures privacy, accuracy, and comfort throughout the procedure. Early assessment helps couples understand male fertility health, identify potential issues, and take timely steps toward conception.
FAQ's
1
Why is a fertility evaluation important for couples?
A fertility evaluation helps identify why pregnancy is not happening and guides the doctor to choose the right treatment quickly. It saves time, money, and emotional stress.
2
How long does a fertility evaluation take?
Most couples complete the basic tests within 1–2 days. Some additional tests may take a week depending on reports.
3
What tests are included in a couple’s fertility check-up?
The evaluation usually includes semen analysis, ovulation check, hormone tests, and an ultrasound to assess reproductive health for both partners.
4
Do both partners need testing?
Yes. Fertility issues can come from the man, the woman, or both. Testing both partners gives a complete picture and helps choose the best treatment.
5
When should a couple see a fertility specialist?
If a couple has been trying to conceive for 12 months (under 35) or 6 months (over 35) without success, they should meet a fertility expert for evaluation.

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