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Intracytoplasmic Sperm Injection (ICSI) Treatment in Mumbai | Advanced Fertility Support for Couples.

Syringe performing injection into an egg cell.

What is Intracytoplasmic Sperm Injection (ICSI)?

Intracytoplasmic Sperm Injection (ICSI) is a highly specialized fertility procedure in which a single sperm is injected directly into an egg to achieve fertilization. This advanced technique is performed in a laboratory and is particularly useful when conventional IVF may not be sufficient. ICSI has transformed fertility treatment for couples facing severe male infertility, fertilization failure, or previous unsuccessful IVF cycles.


Who Might Be Recommended to Have Intracytoplasmic Sperm Injection (ICSI)?

ICSI is generally recommended for couples facing male infertility challenges or previous fertilization issues. This includes men with very low sperm count, poor motility, or abnormal morphology. It may also be advised for couples who experienced failed fertilization during earlier IVF cycles or for those using frozen eggs or sperm.


How Does Intracytoplasmic Sperm Injection (ICSI) Work Step by Step?

The ICSI procedure is precise and carefully monitored. The main steps include:

  • Ovarian stimulation and egg retrieval: Medications stimulate the ovaries to produce multiple eggs, which are collected under mild sedation.

  • Sperm collection and preparation: A single healthy sperm is selected, sometimes surgically retrieved.

  • Sperm injection: The chosen sperm is directly injected into the cytoplasm of each mature egg under a microscope.

  • Embryo culture: Fertilized eggs are monitored in the laboratory to develop into viable embryos.

  • Embryo transfer: The most viable embryo is placed into the uterus to initiate pregnancy.

Each step is carefully controlled to ensure safety and maximize fertilization.


Intracytoplasmic Sperm Injection (ICSI) vs IVF – What’s the Difference?

While both ICSI and IVF involve fertilizing an egg outside the body, the difference is that in ICSI, a single sperm is injected directly into the egg, whereas in conventional IVF, eggs and sperm are mixed together for natural fertilization. ICSI is particularly effective for severe male infertility or previous fertilization failure, while IVF is suitable for couples with less complex fertility challenges.


Can Intracytoplasmic Sperm Injection (ICSI) Help with Severe Male Infertility?

Yes, ICSI is specifically designed to address severe male infertility. By injecting a single sperm directly into the egg, it bypasses issues like low sperm count, poor motility, or abnormal morphology. Many couples who might not have conceived otherwise have successfully achieved pregnancy with ICSI.


How Successful is One Cycle of Intracytoplasmic Sperm Injection (ICSI)?

The success of one ICSI cycle depends on factors such as:

  • Woman’s age: Younger women have higher success rates

  • Egg quality: Healthier eggs increase the chances of fertilization

  • Sperm quality: Viable sperm are essential

  • Overall reproductive health: Conditions like endometriosis or uterine abnormalities may influence outcomes

On average, success rates range from 40% to 50% for women under 35, and careful monitoring by a fertility specialist improves results.


Are There Any Risks or Side Effects of Intracytoplasmic Sperm Injection (ICSI)?

ICSI is a safe procedure, but minor risks can include:

  • Ovarian hyperstimulation due to fertility medications

  • Mild discomfort during egg retrieval

  • Multiple pregnancies if more than one embryo is transferred

Long-term studies indicate that babies born via ICSI are generally healthy. Your fertility specialist will explain all precautions and answer any questions before the procedure.


Is Intracytoplasmic Sperm Injection (ICSI) Right for Us If We Don’t Have Male Infertility?

Even without male infertility, ICSI may be recommended in certain situations, such as previous IVF fertilization failure, use of frozen eggs or sperm, or advanced maternal age. A fertility specialist will evaluate your individual circumstances and advise whether ICSI is appropriate.


What Happens If Intracytoplasmic Sperm Injection (ICSI) Doesn’t Work the First Time?

If ICSI does not result in pregnancy, your specialist will review all contributing factors, including egg and sperm quality, embryo development, and lab conditions. Adjustments may include:

  • Modifying ovarian stimulation protocols

  • Selecting different embryos

  • Refining laboratory techniques

Many couples achieve success in subsequent cycles, and support is provided throughout the process.


How to Prepare for Your Intracytoplasmic Sperm Injection (ICSI) Treatment at Meridian IVF.

Preparation for ICSI includes both medical and lifestyle steps:

  • Follow your doctor’s instructions regarding medications, ovulation monitoring, and sperm collection

  • Maintain a balanced diet and moderate exercise while avoiding smoking or alcohol

  • Manage stress through counseling, meditation, or relaxation techniques

  • Ensure emotional readiness with support from your partner and clinic team

Proper preparation ensures a smooth procedure and improves chances of success.


Why Choose Meridian IVF for Your Intracytoplasmic Sperm Injection (ICSI) Journey

At Meridian IVF, Mumbai, we provide personalized ICSI consultations and treatments using advanced laboratory facilities and expert care. Our compassionate team supports couples throughout every stage, from initial evaluation to embryo transfer and follow-up. With Meridian IVF, you can expect professional guidance, cutting-edge technology, and a comfortable, supportive environment for your fertility journey.

FAQ's

1

What is the difference between IVF and ICSI?

IVF mixes eggs and sperm in a dish for natural fertilization, while ICSI involves directly injecting a single sperm into each egg. ICSI is mainly used for male infertility or previous IVF fertilization failure.

2

What is the downside of ICSI?

ICSI has no major long-term risks, but it may slightly increase the use of fertility medicines and requires advanced lab expertise. However, babies born through ICSI are generally healthy.

3

How long does it take to get pregnant with ICSI?

Typically, one ICSI cycle takes 4–6 weeks, including stimulation, egg retrieval, fertilization, and embryo transfer. Pregnancy results are confirmed 10–12 days after transfer.

4

How much does ICSI cost in India?

The average cost of ICSI in India ranges from ₹1,50,000 to ₹2,50,000, depending on medication needs, age, and treatment complexity.

5

Is ICSI successful the first time?

Success depends mainly on age, egg quality, and sperm health. For women under 35, ICSI success rates are around 40–50% per cycle.

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